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19 With the very first-generation cTnT assay, this issue was compounded by a nonspecific tag antibody that cross-reacted with troponin T in skeletal muscle mass.20 At the time this antibody was replaced by a single with substantial specificity, false-constructive elevations from skeletal muscle mass were eradicated.fifteen Reports utilizing immunohistochemistry and polymerase chain response have verified that these fetal isoforms will not be detected via the assay employed now.21,22 Therefore, the assay utilized to measure cTnT amounts has cardiac specificity equivalent to that of assays for cTnI.
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